This section is used to present feedback and comments from people who have read the published protocol or review. There are three subheadings: Summary, Reply and Contributors. The summary should be prepared by the feedback editor for the CRG in consultation, if necessary, with the person submitting the comment. A reply to this should then be prepared by the author(s) of the review. Details of the people who contributed to this process should be given. Further information on the comments and feedback and the updating of reviews is given in Chapter 10 of the Cochrane Handbook for Systematic Reviews of Interventions (Higgins 2006b).